Towards Systems medicine based on multi-oMics
In December 2024, Nantes University unveiled the five research projects that have been awarded the ‘Labex NExT’ label for the next four years. The Labex NExT are interdisciplinary research projects with a strong structuring effect on the Nantes region. Their aim is to strengthen the excellence and influence of research in the two areas covered by the I-site NExT: health and the industry of the future.
Among the 5 projects selected, each of which will receive 1.8 million euros in funding until 2029, Labex SysMics (Towards Systems medicine based on multi-oMics) has been conceived as a transdisciplinary initiative at the interface between Biology & Health and Digital Sciences, structured around 4 complementary axes:
- Advanced methods and technologies for large-scale biomic screening;
- Interoperable infrastructures for the secure sharing of health research data, in line with international recommendations for open science;
- New computational models for the interpretation of multi-omics data;
- Demonstrators for the integration of multi-scale (longitudinal) data.
By joining forces within the University of Nantes around the integration of multi-omics data, SysMics aims to accelerate the transfer of systems biology approaches into medical practice in order to:
- model disease trajectories using mathematical and artificial intelligence approaches to improve the production of digital twins
- develop in silico diagnostic tools based on open data and open source algorithms
- discover new biomarkers and therapeutic targets to accelerate drug development
- develop decision support tools based on disease risk prediction to promote innovative clinical trials in precision medicine.
SysMics represents a unique opportunity to build such a biomedical ecosystem and position Nantes-U as a leader in systems medicine and digital health.
SysMics is coordinated by Richard Redon, l’institut du thorax.
